Chronic kidney disease (CKD) is a major global public health issue, affecting over 10%1 of the population worldwide. The problem was ranked 16th among the leading causes of death in 2016 and is expected to rise to 5th by 20402, making it a larger problem than heart disease or certain cancers.

Year: 2016 Estimated 2040:
Disease state Leading cause of death Leading cause of death
Chronic Kidney Disease #16 #5
Ischemic Heart Disease #17 #6
Lung Cancer #30 #15
Diabetes #45 #22

And CKD comes with a tremendous cost burden.

Chronic Kidney Disease (CKD): Just the Facts3

15% of U.S. Population

1 in 7 U.S. adults have CKD (without diabetes)

1 in 3 (33% of U.S. population with diabetes, the leading cause)

$70B+ Price Tag

U.S. adults (66+ years) with CKD represent 23.8% of Medicare spending

Double the Per-patient Spending

Annual per-person Medicare spending for patients 66+ with CKD ($23,691) compared with those without CKD ($10,842)

2Foreman KJ, Marquez N, Dolgert A, Fukutaki K, Fullman N, McGaughey M, et al. Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: Reference and alternative scenarios for 2016–40 for 195 countries and territories. Lancet. 2018; 392 (10159): 2052–2090. 10.1016/S0140-6736(18)31694-5 [PMC free article] [PubMed] [CrossRef] [Google Scholar]